Cape Town: Specialist Scientist – Structural Biology & Purification posted by Afrigen Biologics & Vaccines
Posted on 2025-04-29 00:00:00
| Employer | Afrigen Biologics & Vaccines |
|---|---|
| Category | Other Medical |
| Location | Western Cape / Cape Town |
Job Summary
Are you passionate about contributing to global health and vaccine innovation? Afrigen Biologics is seeking a qualified and experienced Specialist Scientist to join our R&D team, providing purification and/or structural biology expertise and support to various development projects. The appointee will also provide technical support to the analytics team where needed. The successful candidate may be involved in training (& mentorship) of scientists/engineers and production staff and contribute to a portfolio of R&D projects. The candidate should be comfortable working in a diverse, interdisciplinary team and managing multiple projects/tasks.
Key Responsibilities:
- Optimisation of mRNA vaccine antigen purification workflow
- Development & optimisation of purification technologies required for pDNA purification.
- Development of purification process trains required for other Afrigen vaccine related products.
- Training of Afrigen scientist on purification and structural biology aspects, both in concept and hands-on training
- Structural biology expertise for functional expression for antigens (mRNA and other)
- Contribute to analytics development, trouble shooting, data analyses where needed and appropriate.
- Excellent organization and time management skills
- Excellent written and verbal communication skills (good writing skills demonstrated through publications)
- Strong interpersonal skills and the ability to work both independently and as part of a team required.
- Proficient in Microsoft Word, Excel, PowerPoint, Outlook, and data entry required.
- Good problem-solving and creative thinking skills and well-developed personal stress management skills.
- Capable of working as part of a multidisciplinary team showing strong communication and interpersonal skills.
- Comply with the companys documentation practices and write progress reports.
- Abide by the companys health and safety policies and procedures
Qualifications and Experience:
- PhD degree in Medical Biochemistry, Biotechnology, Bioprocess Engineering, or related field.
- Minimum of 5 years post-qualification experience in a research and development environment.
- Exposure and understanding of scientific principles that governs production of vaccines and /or biologicals.
- Quality and regulatory compliance knowledge, i.e. SAHPRA and WHO. Knowledge of cGMP (SA, PIC, WHO) and GLP guidelines.
- Knowledge and experience in analytical method development particularly bioanalytics experience will be an advantage.
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