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Cape Town City Centre: GC-MS/Analytical Chemist

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Job Description

About the Role

We are seeking a highly skilled GC-MS/Analytical Chemist to join our team in Cape Town City Centre. As the owner of our Gas Chromatography-Mass Spectrometry (GC-MS) instruments, you will be responsible for the operation, maintenance, troubleshooting, and performance of these instruments. This is an excellent opportunity to work with a dynamic team and contribute your expertise to the development of analytical methods for complex food matrices.

Key Responsibilities

• Own the operation, maintenance, troubleshooting, and performance of GC-MS instruments

• Perform routine and non-routine maintenance (filaments, seals, columns, pumps, values)

• Diagnose chromatographic and MS-related issues efficiently

• Perform qualitative and quantitative chemical analysis with accurate interpretation of data (e.g. ghost peaks, carryover)

• Develop, validate, and optimize analytical methods for complex food matrices

• Support developers with analytical insights

• Maintain accurate documentation, records, and reports

• Calibrate instruments and ensure proper functioning

• Interpret results using laboratory software and identification systems (e.g., MassHunter, NIST, Wiley)

• Analyse volatile and semi-volatile compounds across real-world matrices

• Collaborate with cross-functional teams including NPD, quality assurance, and production

• Sample preparation using appropriate techniques including solvent extraction, headspace GC, SPME

• Investigate and resolve analytical issues and deviations and conduct a root-cause analysis

• Ensure compliance with laboratory quality standards (e.g. ISO)

Requirements

• BSc in chemistry, Analytical Chemistry, or Food Science

• Minimum 2-3 years hands-on proven experience with GC-MS hardware and software within the food industry

• Strong understanding of:

+ Chromatography (column selection, flow, split ratios, temperature programming)

+ Mass spectrometry (ionization, fragmentation, tuning)

• Experience with the use of spectral libraries (NIST & Wiley)

• Good problem-solving, analytical skills with attention to detail and data integrity

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• Hands-on GC-MS experience in a lab setting where you were responsible for data quality (not just running prebuilt methods)

• Experience with additional techniques (e.g., LC-MS)

• Ability to work independently and in a team environment

• Ability to take ownership of the instrumentation

• Strong problem-solving mindset with focus on root-cause analysis, communication, and report-writing skills

Qualifications

None mentioned.

Salary & Benefits

Industry-related salary based on experience.

How to Apply

Click the green “Go Apply” button below to apply directly online with the employer.

About Scientific / QA Jobs in Cape Town Region

The Cape Town region is home to a thriving scientific and QA (Quality Assurance) community, with many organizations across various industries seeking skilled professionals to drive innovation and quality control.

Typically, salaries for scientific and QA roles in the Cape Town region vary widely depending on factors such as experience, company size, and industry sector. Generally, entry-level positions may command salary ranges between R300 000 to R500 000 per annum, while senior roles can offer more substantial packages, often ranging from R600 000 to R1 200 000 or more, with variations based on individual circumstances.

Common skills required for scientific and QA roles include a strong foundation in mathematics and science, programming languages such as Python, Java, or C++, data analysis and interpretation, attention to detail, effective communication, and the ability to work collaboratively as part of a team. Additionally, many organizations in this sector place a high value on analytical thinking, problem-solving skills, and adaptability.

The Cape Town region is home to various industries that commonly employ scientific and QA professionals, including the technology industry, financial services sector, manufacturing sector, and research institutions. While these sectors may have varying requirements, many organizations in these areas seek skilled professionals to drive innovation, quality control, and data-driven decision-making.

For those seeking a career in scientific or QA roles, there are numerous opportunities for professional growth and development. Typically, professionals in this field can expect to move into senior roles with increased responsibility within 5-10 years of experience. Many organizations also offer training and development programs, mentorship opportunities, and networking events to support the ongoing education and skills enhancement of their employees.

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As a job seeker, it is essential to research the specific requirements of various industries and companies to determine which role best aligns with your skills, interests, and career goals. By understanding the general trends in the scientific and QA job market, you can position yourself for success in this rewarding field.


This information provides general career guidance. Actual salaries and requirements vary by employer.



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